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KMID : 1094020080250060523
Journal of Veterinary Clinics
2008 Volume.25 No. 6 p.523 ~ p.525
Sertoli Cell Tumor Accompanied by Pancytopenia in a Dog
Choi Ul-Soo

Kim Hyun-Wook
Choi Ji-Hye
Kim Hye-Jin
Jang Jae-Young
Lee Chang-Woo
Abstract
11 year old male Yorkshire terrier was referred to Haemaru Referral Animal Hospital with signs of hematuria, petechia, and gynecomastia. Blood works revealed severe leukopenia, moderate anemia and severe thrombocytopenia. On ultrasonography and radiography, mixed echo texture mass was found in abdomen. The abdominal mass was surgically removed, and submitted for histopathology. Histopathologic features of the tissues were consistent with malignant Sertoli cell tumor. Bone marrow aspirates were hypocellular. Serum estrogen concentration was 72.80 pg/ml (normal range for females <15 pg/ml) after surgery. Clinical signs of feminization and hemorrhagic diathesis were attributed to hyperestrinism caused by the tumor. The dog was put on fluid therapy, antibiotics and palliative drugs and survived 2 more weeks after surgery without clinical improvement.
KEYWORD
Sertoli cell tumor , pancytopenia , dog
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